A Student Questions Take Home Exam - 1786 Words

Bio 5309 Graduate Student Questions Take Home Exam 1 Fall 2016 Question There’s a lot of excitement these days about a type of cellular immunotherapy known as CAR-T, a method of modifying peoples’ immune cells to fight cancer. But you could also fill a book listing all the problems its makers will have to solve—how to test, manufacture, and even the define the nature of these cancer-killing cells—before the CAR-T story is a successful one. Is the following statement true or false? Why? â€Å"The cells that are delivered back into the patient are not what ends up doing the bulk of the therapeutic work.† INTRODUCTION The genetic modification and characterization of T-cells with chimeric antigen receptors (CARs) allow functionally distinct T-cell subsets to recognize specific tumor cells. The incorporation of costimulatory molecules or cytokines can enable engineered T-cells to eliminate tumor cells. CARs are designed in a modular fashion and generated by fusing the antigen-binding region of a monoclonal antibody (mAb); extracellular target-binding domain to a transmembrane domain and intracellular-signaling domains. They have shown clinical benefit in patients treated with CD19-directed autologous T-cells. Recent successes suggest that the modification of T-cells with CARs could be a powerful approach for developing safe and effective cancer therapeutics (Dai et al 2016). Chemotherapy and radiation have been used for treatment of cancer since long time but many of theShow MoreRelatedStandardized Testing in Saudi Arabia1435 Words   |  6 Pagespeople can demonstrate justice to include education. Specifically, there are numerous students and teachers who suffer every day from injustice. Some students suffer from the weak education system in their countries while others suffer from mistreatment by their teachers. This alone is an injustice because students attend schools and universities in order to be good people for their countries in the future, and students expect their teachers and administrators to provide a good learning environment forRead MoreCommon Core Is A Hassle Throughout The Nation1717 Words   |  7 Pagesin schools. Common Core implements more rigorous standards, even though students are already having trouble with previous standards. Common Core state standards are an attempt to make American schools compete with the best education s ystems worldwide (Avoid). Implementing the use of more technology, incorporating more critical thinking questions, and having to apply the knowledge to tasks in the tests shows a change students aren’t ready for. The change happened too quickly when Florida signed inRead MoreAre Standardized Exams Sufficient as a Test of Knowledge?1186 Words   |  5 Pageseducation is whether standardized exams are a good way to test the knowledge of a student and whether they should be given in a school to determine if a child advances. Standardized exams are a subject many people feel very strongly about. Some believe that it is stressful and time consuming; others consider that it can be beneficial. I believe that standardized exams should not be given to students and should not be used to determine the knowledge of students or advancement to the next grade levelRead MoreCheating, Its Consequences, And Findings On Cheating1685 Words   |  7 PagesExecutive Summary: The purpose of this paper is to discuss the practice of cheating and its consequences in the graduate students. Lot of papers, scholarly articles have been written around this topic describing the behavior and attitude of the students towards the practice of cheating. There are various factors that can force the students to cheat, irrespective of which the student is expected to submit genuine work of his own to the school. This paper discuss few of the main reasons behind the practiceRead MoreEducation in Vietnam vs America Essay1219 Words   |  5 PagesPhung Nguyen English 112 D18 Professor William December 10, 2014 Education System in Vietnam versus in America â€Å"The United States system of education that has been created for students in Kindergarten through High School is the best educational system in the world. No exceptions. No disclaimers. No doubt. It is simply the best† (Pat Quinn). This means that in many other countries, especially developing countries, the education systems are still old, and Vietnam is one of those countries. AlthoughRead MoreHonors Honor Code And Academic Integrity1084 Words   |  5 Pagesapproximately 5,400 undergraduate students and 2,700 graduate students. Princeton’s Honor Code was created in 1893 and functions to uphold academic integrity at the university. They abide by an Honor Code Constitution that has been revised throughout the years. Students can access their rights in a document entitled Rights, Rules, and Responsibilities. The Honor Code applies to all in class assessments such as tests, quizzes, and in-class papers. Before students take exams, they pledge that they â€Å"willRead MoreInformation Flow, Utilization And Business Value1749 Words   |  7 PagesIT ecosystem and gets the correct links for establishing services, providing training and also staffing for their clients. ABOUT THE PROJECT: This project is based on creating a website for conducting examinations online. Currently conducting exams to employees manually is becoming overhead because of maintaining the material and there is possibility of leaking of paper. Security is also one of the main problem, to maintain security it includes money and man power, there is loss in terms of moneyRead MoreOnline Learning Is Good Or Traditional Learning?847 Words   |  4 Pagesmany things like banking, shopping, and communication using technology in our daily lives. And, the next big thing, which has been growing very fast, is online learning. It is very easy to take online classes via internet. People taking online classes do not go to a college campus, so they do everything from home using technology. Some people think that online learning is not good because it has many drawbacks. For example, online learning involves cheating and lack of class interaction, so they doRead MoreHandout 01BOSTON UNIVERSITYDepartment Of Me chanical EngineeringMechanics1188 Words   |  5 Pagesbarbone@bu.edu. Website: http://learn.bu.edu Text: Sanjay Govindjee, Engineering Mechanics of Deformable Solids, Oxford; 2013. ISBN: 978-0-19-965164-1 Grading: Approximate allocations of credit for work for the semester is as follows: Midterm exam: Final Exam: Design and Project Assignments: Laboratory Reports from Demonstrations (3): Quizzes: Teaching Fellows: Saman Seifi ’Lekan Babaniyi 20% 20% 20% 20% 20% samansei@bu.edu lekanb@bu.edu Important Information: †¢ Failure to turn in any one of theRead MoreAp Psychology1425 Words   |  6 PagesAP Psychology Free Response Questions Sample The following questions are samples of the free response questions from past AP Psychology exams. The free response sections are worth 33 1/3 percent of the total grade. Students have 50 minutes to answer two questions. The key to successfully answering these questions is to: completely define the terms using appropriate psychological terminology and then critically apply each term. Many students concentrate their efforts on the multiple-choice